The small village of Muslone has a fascinating history: it was established as an autonomous fief in 1421 and maintained its autonomy in 1817 when it joined the Municipality of Gargnano. The church was then built and dedicated to Saint Matthew and dates back to the first feudal lord of the village Maffeo de Medalli da Gargnano. It welcomes tourists from the square. Once inside, the particular shape of the presbytery can be noted. It slants to the left to symbolize the tilted head of Christ on the Cross. The main altar is adorned with a painting depicting the Madonna in Glory with Saint Matthew and Two Holy Bishops, created at the beginning of the seventeenth century by the painter Andrea Bertanza. It is framed in a stucco soasa frame. Another painting, the Baptism of Christ, by the same artist adorns the baptistery.
The church also has some lateral altars: the altar of the Madonna with the Rosary, which includes a seventeenth century altarpiece, the altar of Saint Rocco and Saint Anthony, and the altar of the Immaculate Conception, which preserves a wooden statue of the Madonna made in 1521 by the Milanese sculptor Pietro Bussolo.